• Green tea. Another tea that's shown to be effective at combating cold sores, green tea is rich in an antioxidant called epigallocatechin gallate, or EGCG, which is thought to have antiviral properties. In a November 2012 study published in the journal Food and Chemical Toxicology, scientists from Georgia Health Sciences University discovered that EGCG reduced the proliferation of herpes type 1 cells by 92 percent. However, they also found that a modified, synthetic form of EGCG, p-EGCG, reduced infectious cells almost 100 percent. The authors of that study have since developed a p-EGCG-containing cream that's available over the counter called AverTeaX Topical Ointment. Two to 3 cups of green tea per day, or green tea compresses on a cold sore, will give you high levels of EGCG.
• Zinc. Though the jury's out as to whether zinc will do anything for your cold, it could make a cold sore go away faster. Test-tube studies have shown that zinc can kill up to 98 percent of herpes simplex type 1 cells, but real-world studies haven't been as conclusive. One study suggests that topical zinc oxide ointment reduced cold-sore duration by up to two days, and the authors of that study had their participants use the ointment every two hours as soon as they felt a cold sore coming on.
• Honey. This treatment could be better than drugs, according to research from the United Arab Emirates. In a small study of 16 people, the researchers found that topical applications of honey shortened the duration of cold sores 35 percent better than acyclovir, the active ingredient in prescription herpes antiviral treatments. Research from New Zealand found that four different types of honey were able to kill the virus in test tubes, suggesting that any unprocessed, raw honey (which has the highest levels of antiviral compounds) might help treat a cold sore.
None of these treatments will prevent you from ever having another cold sore, and you can still shed, or transmit, the virus when cold sores are developing. But any one of these is certainly less expensive than a prescription or over-the-counter cold-sore medication—and will have you back to your smiling self as soon as possible.